Bicarbonate

About Test

The Bicarbonate assay measures the level of bicarbonate ions in the bloodstream, which play a critical role in maintaining the body's acid-base balance. Bicarbonate is a key component of the body's buffering system, helping to regulate pH levels and counteract acidic conditions. This test is essential in assessing various conditions, including acidosis, alkalosis, kidney disease, and respiratory disorders. Physicians may order this test as part of a metabolic panel to evaluate electrolyte balance and kidney function. Elevated levels may indicate metabolic alkalosis, while low levels could signal metabolic acidosis or respiratory alkalosis. Monitoring bicarbonate levels is crucial for managing conditions such as chronic kidney disease, diabetes, and respiratory disorders to ensure proper acid-base equilibrium and overall health.

Sample Requirements

Gold SST Tube

Stability

Serum: 1 day 20-25°C, 7 days 2-8°C

Turnaround Time

4 hours

Gold SST Tube

Assay Interferences

Interferences (Up to 10%)

Ascorbic Acid: 30 mg/dL

Bilirubin (conjugated): 50 mg/dL

Bilirubin (unconjugated): 40 mg/dL

Haemolysis: Haemoglobin <500 mg/dL.

Lipemia: 1400 mg/dL

Other: In very rare cases gammopathy, may cause unreliable results.

Reference Range (mmol/L):

22.0 – 29.0

Known factors:

Decreased Bicarbonate

  • Problem: Incorrect storage
    Caused by: Unseparated sample in fridge / Leaving samples open to air

Critical Value:

Below 20 mmol/L or Above 40 mmol/L