CK-NAC

About Test

The Creatine Kinase (CK) assay measures the levels of CK, an enzyme found predominantly in muscle tissue, in the bloodstream. This test is vital for assessing muscle health and diagnosing various medical conditions affecting muscles, including muscle injury, inflammation, or diseases such as muscular dystrophy. CK plays a crucial role in energy production within muscle cells, and its levels in the blood rise following muscle damage or breakdown. Elevated CK levels are often observed after strenuous exercise, trauma, or surgery involving muscles. Additionally, certain medical conditions such as myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), or inflammatory myopathies may also cause increased CK levels. Conversely, low CK levels are less common but could indicate severe muscle wasting or conditions affecting CK production. Doctors frequently order CK testing to evaluate patients with muscle-related symptoms such as muscle pain, weakness, or swelling, helping to diagnose and monitor various muscle disorders.


Sample Requirements

Gold SST Tube

Stability

Serum: 2 days 20-25°C, 7 days 2-8°C

Turnaround Time

4 hours

Gold SST Tube

Assay Interferences

Interferences (<10% up to)

Ascorbic acid: 30 mg/dL 120 IU/L, 65 mg/dL 296 IU/L

Bilirubin (conjugated): 55 mg/dL 120 IU/L, 65 mg/dL 298 IU/L

Bilirubin (unconjugated): 48 mg/dL 120 IU/L, 65 mg/dL 285 IU/L

Hemoglobin: 100 mg/dL 140 IU/L, 180 mg/dL 304 IU/L

Lipemia: 1600 mg/dL 120 IU/L, 1800 mg/dL 262 IU/L

Other: Rarely, gammopathy, may cause unreliable results.

Reference Range (IU/L):

Male: 20.0 – 215.0 (race dependent) / Female: 20.0 – 160.0 (race dependent)


Critical Value:

Above 5000 IU/L