Folate (serum)

About Test

The Folate (serum) test measures the level of folate, a B-vitamin, in the blood. Folate, also known as vitamin B9, is essential for the production of red blood cells, DNA synthesis, and proper cell division. It is particularly important during periods of rapid growth, such as pregnancy, and plays a key role in the prevention of certain birth defects.

This test is commonly used to diagnose folate deficiency, which can lead to symptoms such as fatigue, weakness, irritability, and in severe cases, megaloblastic anaemia—a condition where red blood cells are larger than normal and not fully developed.

Key Uses of the Folate (serum) Test:

  1. Diagnosing Folate Deficiency: Low folate levels can result from poor dietary intake, malabsorption conditions (such as coeliac disease), or increased demand during pregnancy.

  2. Monitoring Nutritional Status: The test helps assess an individual's nutritional status, especially in people at risk of deficiency, such as those with gastrointestinal disorders, alcohol dependency, or poor diets.

  3. Evaluating Anaemia: Folate deficiency is often linked to certain types of anaemia, particularly megaloblastic anaemia, where red blood cells are abnormally large and underdeveloped.

Monitoring folate levels ensures that healthcare providers can diagnose deficiencies early, guide dietary recommendations, and, if necessary, prescribe folic acid supplements to maintain overall health and well-being.


Sample Requirements

Gold SST Tube

Stability

Serum: 7 days 2-8°C

Turnaround Time

4 hours

Gold SST Tube

Assay Interferences

Interferences (Up to 5%)

Calcium: Above 15 mg/dL

Potassium: Above 7 mmol/L

Sodium: Above 180 mmol/L

Iron: Above 800 ug/dL

Zinc: Above 500 ug/dL

Magnesium: Above 4 mg/dL

Copper: Above 600 ug/dL

Bilirubin (conj): Above 15 mg/dL

Lipemia: Above 600 mg/dL

Haemolysis: Above 2 g/L

Reference Range (ug/L):

1.5 - 20.0


Critical Value:

Not applicable