Lactate Dehydrogenase (LDH)

About Test

The Lactate Dehydrogenase (LDH) assay measures the activity of the enzyme LDH, which plays a key role in anaerobic metabolism and tissue damage. LDH is present in various tissues throughout the body, including the heart, liver, kidneys, skeletal muscle, and red blood cells. This test is valuable in diagnosing and monitoring a wide range of conditions, including myocardial infarction, liver disease, muscle injury, hemolysis, and certain cancers. Elevated LDH levels may indicate tissue damage, inflammation, or cell death in affected organs or tissues. Physicians often utilize LDH testing in conjunction with other diagnostic tests to assess disease severity, monitor treatment response, and track disease progression. Additionally, LDH levels may provide prognostic information in certain conditions, helping healthcare providers anticipate outcomes and plan appropriate interventions. Regular monitoring of LDH levels is essential for effectively managing various medical conditions and optimizing patient care.


Sample Requirements

Gold SST Tube

Stability

Serum: 4 days 2-8°C

Turnaround Time

4 hours

Gold SST Tube

Assay Interferences

Interferences

Lipemia: Interference less than 3% up to 1000 mg/dL Intralipid

Icterus: Interference less than 3% up to 40 mg/dL or 684 umol/L bilirubin

Other: Highly lipemic samples may exceed the reaction absorbance and will have to be diluted and re-run.

Reference Range (IU/L):

Children: 60.0 – 170.0 / Adult 16-59 years: 45.0 – 90.0 / Adult ≥60 years old: 55.0 – 100.0


Critical Value:

Not Applicable