SHBG

About Test

The Sex Hormone-Binding Globulin (SHBG) test measures the level of SHBG, a protein produced by the liver that binds to sex hormones, including testosterone and oestrogen, in the blood. SHBG regulates the amount of free, biologically active sex hormones available to tissues and helps maintain hormonal balance.

This test is commonly used to evaluate conditions related to hormone imbalances, such as polycystic ovary syndrome (PCOS), thyroid disorders, and conditions involving abnormal levels of sex hormones. Elevated SHBG levels can be associated with conditions such as hyperthyroidism, liver disease, or oestrogen dominance. Conversely, low SHBG levels may indicate conditions like hypothyroidism, obesity, or androgen excess.

Monitoring SHBG levels helps healthcare providers assess hormonal health, diagnose endocrine disorders, and guide treatment strategies to balance hormone levels effectively. Regular testing is important for managing conditions related to hormonal imbalances and supporting overall health and well-being.

Sample Requirements

Gold SST Tube

Stability

Serum: 3 days at 2-8 °C, 1 month at -20 °C (± 5 °C)

Turnaround Time

4 hours

Gold SST Tube

Assay Interferences

Recovery within ± 10 %

Bilirubin: < 1026 umol/L

Hemolysis: < 1.8 mmol/L

Lipemia: < 2700 mg/dL

Biotin: < 246 nmol/L

Rheumatoid Factors: 1160 IU/mL

Reference Range:

Male:

<50 yo: 15-64 nmol/L
>50 yo: 14-78 nmol/L

Female:

<50 yo: 19-145 nmol/L
>50 yo: 14-136 nomol/L

Critical Value:

Not applicable