Unsaturated Iron Binding Capacity (UIBC)

About Test

The Unsaturated Iron Binding Capacity (UIBC) test measures the amount of iron-binding sites available in the blood serum that are not currently occupied by iron. It is part of a group of tests used to assess iron metabolism and diagnose iron-related disorders.

The UIBC test is typically performed alongside other tests, such as serum iron and total iron-binding capacity (TIBC), to provide a comprehensive evaluation of iron status.

Key Points of the UIBC Test:

1. Iron Binding Capacity: UIBC indicates how much more iron the blood can bind. It reflects the reserve capacity of transferrin, the protein that transports iron in the bloodstream.

2. Diagnosis of Iron Deficiency: Elevated UIBC levels often suggest iron deficiency, as there are more unoccupied binding sites available. This can help diagnose conditions such as iron deficiency anaemia.

3. Assessment of Iron Overload: Low UIBC levels may indicate iron overload conditions, such as haemochromatosis, where excessive iron is present and saturates the binding sites.

4. Comprehensive Iron Testing: The UIBC test is used in conjunction with serum iron and TIBC tests to provide a fuller picture of iron metabolism and status in the body.

Monitoring UIBC levels helps healthcare providers evaluate iron status, diagnose iron-related disorders, and guide appropriate treatment strategies, such as iron supplements or dietary adjustments.