Vitamin B12 (total)
About Test
The Vitamin B12 (total) test measures the level of vitamin B12 in the blood. Vitamin B12 is an essential nutrient that plays a crucial role in red blood cell formation, DNA synthesis, and the proper functioning of the nervous system. It is obtained primarily through dietary sources such as meat, fish, dairy products, and fortified foods.
This test is commonly used to diagnose and monitor vitamin B12 deficiency, which can lead to symptoms such as fatigue, weakness, memory loss, and neurological issues like numbness or tingling. Deficiency can be caused by various factors, including poor dietary intake, absorption issues, or certain medical conditions such as pernicious anaemia or gastrointestinal disorders.
Monitoring vitamin B12 levels helps healthcare providers assess nutritional status, diagnose deficiencies, and guide appropriate treatment, such as dietary adjustments or vitamin B12 supplements, to maintain overall health and prevent complications associated with deficiency. Regular testing is important for individuals at risk of vitamin B12 deficiency or those undergoing treatment for related conditions.
Sample Requirements
Gold SST Tube
Stability
Serum: 2 hours at 15-25 °C, 48 hours at 2-8 °C,
56 days at -20 °C (± 5 °C)
Turnaround Time
8 hours
Assay Interferences
Recovery within ± 10 %
Bilirubin: < 1112 umol/L
Hemolysis: < 0.025 mmol/L
Lipemia: < 17.1 mmol/L
Biotin: < 205 nmol/L
Rheumatoid Factors: 1500 IU/mL
Others: IgG ≤ 28 g/L, IgA ≤ 16 g/L and IgM ≤ 10 g/L
Reference Range (ng/L):
180 - 2000
Critical Value:
Not applicable